That sounds great, definetely what BfA needs for an advanced workflow. – Unfortunately I don´t have as much time like you´re quoting to spend and also feel, that I don´t have enough experience working in BfA/Blender to make really useful decisions here.
Maybe you can explain the process of remapping the hotkeys a bit more in detail? I guess there is a faster way than going over the menu in the internal user preferences one by one?